Histamine Intolerance


This nutrigenomics test is for individuals experiencing high histamine or allergic type symptoms – itching, sneezing, wheezing, swelling, headaches or digestive issues. Analyses the key genes and nutrients involved in histamine metabolism.

  • Experiencing skin irritation or breathing difficulties (mimicking an allergic reaction)
  • Experiencing digestive problems or headaches
  • Experiencing insomnia or anxiety

Histamine has many functions: as a neurotransmitter, communicating messages to and from the brain and nervous system; triggering the release of stomach acid to help digestion; and it can also be released after stress, injury or allergic reaction as part of the body’s immune response.

Histamine intolerance is the body’s reaction to an imbalance between accumulated histamine and the capacity to break it down. When the body is unable to break histamine down quickly enough it becomes toxic. Symptoms of histamine toxicity may include skin irritation or breathing difficulties (mimicking an allergic reaction), digestive problems, headaches, insomnia and anxiety.

The Histamine Intolerance test analyses the genes and nutrients needed to breakdown and remove histamine, showing where disruptions occur and how to support optimal function. Diamine oxidase (DAO), which primarily breaks down histamine in the gut, can be impaired by gastrointestinal disease or ‘blockers’ such as alcohol, smoked or fermented foods, black tea, green tea and some medications such as non steroidal anti-inflammatory medications (ibuprofen or aspirin). Insufficient histamine-n-methyl- transferase (HNMT) in the nervous system and lungs can also lead to histamine overload.


Nervous, Immune: HNMT, MAOB and NAT2
Methylation: MTHFR
Gastro Intestinal: ALDH2, DAO and GPX1

Extra nutrigenomics reports can be added up to 6 monhts from the date of the original test.


Client data is securely stored and protected using the highest industry standards. The test is used only to create the reports. The test sample is detroyed after 3 months, and the data after 6 months.

Mouth swab.

Abstain from eating or drinking at least 1 hour before testing.

14 working days after sample reciept