Detoxification

£249.00

For detoxification, including alcohol, pesticides, moulds, air pollutants, heavy metals, hormones, neurotransmitters, and some medications. Detailed report of key genes for phase I, II and III pathways, as well as antioxidant systems for neutralising free radicals.

Category:
  • Experiencing allergies, skin diorders
  • Experiencing headaches, muscle aches, fatigue
  • Experiencing low stress tolerance

Detoxification is the physiological removal of toxic substances from the human body. It is mainly carried out by the liver, and to a lesser extent the small intestine, kidneys and lungs. Substances such as nutrients, food additives, pesticides, medications, air pollutants, alcohol and hormones are transformed from being fat-soluble to water-soluble, allowing them to be more easily excreted from the body. The process occurs in two major phases: Phase I primes toxic molecules for deactivation and Phase II finishes the deactivation and prepares for elimination.

Poor detoxification can cause symptoms such as headaches, muscle aches, fatigue, allergies, skin disorders, weight gain, bloating, acid reflux and heartburn, excessive sweating, chronic infections, subfertility, low libido, poor mental function and low stress tolerance.

The Detoxification test examines genes which impact Phase I reactions in the liver, including the cytochrome P450 oxidases, Phase II conjugation, including the UDP-glucuronosyltransferases (UGTs) and glutathione S-transferases (GSTs) and the Phase III antiporter gene ABCB1, which affects the transport of medicines and other substances into and out of cells. It also include genes that help to neutralise ROS – due to toxic intermediates (generated in Phase 1). The report identifies personalised nutritional support required to optimise detoxification.

GENES INCLUDED

CYP450s: CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2C9, CYP2C19, CYP2D6, CYP2E1 and CYP3A4
Alcohol: ADH1B, ADH1C and ALDH2
Pesticides: PON1
ROS: SOD2, GPX1 and NQO1
Glucuronidation: UGT1A1, UGT1A6
Methylation: COMT and TPMT
Sulphonation: SULT1A1, SULT1E1 and SULT2A1
Acetylation: NAT1 and NAT2
Glutathione: GSTM1, GSTP1 and GSTT1
Antiporter: ABCB1

Extra nutrigenomics reports can be added up to 6 monhts from the date of the original test.

PRIVACY + SECURITY

Client data is securely stored and protected using the highest industry standards. The test is used only to create the reports. The test sample is detroyed after 3 months, and the data after 6 months.

Mouth swab.

Abstain from eating or drinking at least 1 hour before testing.

14 working days after sample reciept